Adinah's Farm on the corner of Avenue C and East 2nd Street has a remarkable quantity of high quality (and somewhat pricy) grocery products packed into a relatively small place. This family-run grocers also runs a full deli serving breakfast, lunch, and dinner items and houses just about everything you think you suddenly need at 2am at night-- that's right, this place is open 24/7 seven days a week, and the store's staff handles the round the clock schedule marvelously.
And the best thing of all-- cup of coffee here goes for a buck.